Glutathione (GSH) is a naturally occurring tripeptide composed of glutamate, cysteine, and glycine. It is widely studied in biochemistry and cellular biology for its essential role in cellular redox balance and antioxidant defense mechanisms.
What It Is
Glutathione is a key intracellular antioxidant present in most living cells. It functions as a reducing agent, helping to stabilize reactive molecules and maintain cellular function. It exists in two primary forms:
Reduced glutathione (GSH) — active form
Oxidized glutathione (GSSG) — formed after neutralizing oxidative species
Chemical & Structural Properties
Molecular formula: C₁₀H₁₇N₃O₆S
Structure: γ-glutamyl–cysteinyl–glycine
Form: White crystalline or lyophilized powder
Quantity:1500 mg per vial
Purity:≥99% (research-grade)
Biological Role (Research Context)
Glutathione is extensively investigated for:
Redox homeostasis and oxidative balance
Reactive oxygen species (ROS) neutralization
Detoxification pathways (phase II metabolism)
Protein regulation via S-glutathionylation
Cell signaling and apoptosis mechanisms
Mechanistic Areas of Study
Research commonly focuses on:
Oxidative stress and antioxidant systems
Glutathione-dependent enzyme systems (GPx, GR, GST)
Cellular defense and detoxification pathways
Mitochondrial function and energy metabolism
Biochemical pathway regulation in experimental models
Laboratory & Research Applications
Used in controlled research environments for:
Cell culture and biochemical assays
Oxidative stress studies
Toxicology and detoxification research
Analytical chemistry (HPLC, mass spectrometry)
Thiol–disulfide exchange experiments
Handling & Storage (Research Settings)
Store in a cool, dry, light-protected environment
Refrigerate (2–8°C) for short-term or freeze for long-term storage
Protect from oxidation, especially in solution
Prepare fresh solutions when required
Important Notice
This product contains 1500 mg of Glutathione and is intended for research purposes only. It is not for human consumption.
$60.00
3 in stock
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