GHK-Cu (Glycyl-L-histidyl-L-lysine copper complex) is a naturally derived tripeptide bound to copper (Cu²⁺). It is widely studied in biochemistry, cell biology, and regenerative research for its role in metal ion transport, cellular signaling, and extracellular matrix dynamics.

What It Is

GHK-Cu is a copper-binding peptide complex formed when the tripeptide GHK (glycine–histidine–lysine) binds to a copper ion. It occurs naturally in biological systems and is investigated for its involvement in cellular repair mechanisms and biochemical regulation.

Chemical & Structural Properties

• Peptide sequence: Gly–His–Lys
• Complex: Bound to copper ion (Cu²⁺)
• Molecular formula: C₁₄H₂₄N₆O₄Cu
• Form: Lyophilized powder (typically blue to blue-violet in solution)
• Quantity: 1000 mg per vial
• Purity: ≥99% (research-grade)

Biological Role (Research Context)

GHK-Cu is studied in experimental systems for:

• Copper ion transport and delivery
• Cellular signaling and gene expression modulation
• Extracellular matrix regulation (collagen, elastin, glycosaminoglycans)
• Cell proliferation and migration
• Antioxidant and oxidative stress-related mechanisms

Mechanistic Areas of Study

Research commonly focuses on:

• Fibroblast activity and tissue-related pathways
• Wound-healing models (in vitro / animal studies)
• Angiogenesis (new blood vessel formation)
• Inflammatory response modulation
• Peptide–metal interaction dynamics

Laboratory & Research Applications

Used in controlled research environments for:

• Cell culture experiments
• Biochemical and molecular assays
• Peptide–metal interaction studies
• Regenerative and tissue modeling research
• Analytical and experimental protocol development

Handling & Storage (Research Settings)

• Store at −20°C or lower
• Protect from light, heat, and moisture
• Reconstitute using sterile laboratory-grade solvents or buffers
• Avoid repeated freeze–thaw cycles
• Follow aseptic laboratory procedures

Important Notice

This product contains 1000 mg of GHK-Cu and is intended for laboratory research purposes only.
It is not for human consumption.